MCMXVI - Massachusetts Institute of Technology by Mads Pedersen
The roman numeral MCMXVI is the year Massachusetts Institute of Technology (aka MIT) moved its campus from Boston to the present location in Cambridge. Given the nature of the going-ons under the dome, it is not surprising to find out that once the inscription was hacked to read IHTFP instead. More like this at hacks.mit.edu. And in case you're wondering MCMXVI = 1916 :-D